Flexeril Cyclobenzaprine Hcl: Uses, Dosage, Side Effects, Interactions, Warning

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine.

Also, methocarbamol and cyclobenzaprine are not recommended in pregnant women, elderly adults, and young children. Flexeril (generic name cyclobenzaprine) does flexeril help with period cramps was developed in the 1970s. Flexeril works on the central nervous system to reduce motor activity or muscle contractions, thus, relieving muscle spasms.

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Multiple drug ingestion (including alcohol) is common in deliberate cyclobenzaprine overdose. As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring is required as soon as possible. The acute oral LD50 of FLEXERIL is approximately 338 and 425 mg/kg in mice and rats, respectively.

Before taking cyclobenzaprine,

If your dose is different, do not change it unless your doctor tells you to do so. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

As with all medications, the costs of cyclobenzaprine can vary.
Between the generics, tizanidine may be slightly more expensive than cyclobenzaprine.
The two main possible complications of taking muscle relaxers are the potential for overdose and dangerous interactions with alcohol.
Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
Skelaxin and Flexeril are most commonly prescribed as their generic counterparts, metaxalone and cyclobenzaprine.
Also, cyclobenzaprine can cause dry mouth because it has anticholinergic effects.

I was unaware of any widespread reports concerning any safety issues with it. As most muscle relaxers act as sedatives, some people take muscle relaxers alone or in combination with other drugs for nonmedical reasons to produce or enhance feelings of euphoria and dissociation. If you’re taking a prescription muscle relaxer, you shouldn’t consume alcohol. Alcohol and muscle relaxers are both depressants, which means they slow down your central nervous system.

It is intended for general informational purposes and is not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. Flexeril is structurally similar to tricyclic antidepressants (such as amitriptyline and nortriptyline). Because of this, there is an increased risk of seizures when taken with tramadol. There are anecdotal reports that cyclobenzaprine or Flexeril has been abused for recreational purposes, as it can potentially lead to an intense relaxation similar to narcotics.

Side Effects

It’s believed to work by attaching to a receptor or protein in the brain called the alpha-2 receptor, which reduces the release of substance P in your brain and spinal cord. Substance P is a chemical that helps increase pain signals to and from the brain. The most common side effects of Flexeril are drowsiness, dizziness, headache, and dry mouth.

It is not known whether this drug is excreted in human milk. Because cyclobenzaprine is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, caution should be exercised when FLEXERIL is administered to a nursing woman. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Flexeril.

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The way they work is not completely understood, but may be due to central nervous system (CNS) depression and sedative effects. These medications do not act directly on the muscle or nerves. It is also chemically like tricyclic antidepressants, so it has a similar action, although it does not have exactly the same effects. By slowing down neuron impulses, cyclobenzaprine stops skeletal muscle spasms, making it a good short-term treatment for minor, but painful, injuries to this system.

Cyclobenzaprine Hydrochloride

In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration. Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin). Physostigmine is not recommended except to treat life-threatening symptoms that have been unresponsive to other therapies, and then only in close consultation with a poison control center. Pharmacologic similarities among the tricyclic drugs require that certain withdrawal symptoms be considered when FLEXERIL is administered, even though they have not been reported to occur with this drug.